LIPORASE (Hyaluronidase) 1500U




In recent years, fillers based on hyaluronic acid have received special recognition in aesthetic medicine due to their almost complete safety for the human body. However, crosslinking of the polymer with BDDE cross-linking agent, which is considered the least toxic, can have negative consequences after hyaluronic acid treatments.

However, due to some reasons, patients are not always satisfied with the results they have received and want to get rid of the filler as soon as possible. Magic remedy Liporase 1,500 I.U of Hyaluronidase can help out here!

Liporase hyaluronidase in the fight against excess hyaluronic acid

The fastest and most effective means of solving the incorrectly, excessively, or unevenly injected hyaluronic acid filler is hyaluronidase – a group of enzymes due to which hyaluronic acid in the body is split into oligomers – low molecular weight fragments.

The South Korean medication Liporase contains a highly active depomilizing enzyme of hyaluronidase 1500 U was elaborated to dissolve hyaluronic acid-based derma filler. In addition, the drug increases the viscosity of hyaluronic acid, which promotes changes in the dermis and connective tissue, and improves the permeability of cell membranes.

Administration of Hyaluronidase Liporase

Hyaluronidase Lipoise is synthesized in the cytoplasm of cells and the intercellular space of the human body. It is a versatile enzyme with a broad spectrum of action, which increases the bioavailability of many drugs administered subcutaneously or intramuscularly.

In cosmetology, the drug has particular success in the rapid elimination of hyaluronic acid in order to avoid undesirable consequences from injection procedures. Liporase is not suitable for correcting excessive amounts of silicone, collagen, lactic acid, and calcium hydroxyapatite, as well as for hypersensitivity to them.

Among the main indications for the introduction of hyaluronidase Liporase are:

  • treatment of fibrous cellulite and granulomas;
  • reducing the risk of edema and fibrosis after lipoplasty of the breast and chin area;
  • correction of excess hyaluronic acid;
  • prevention of necrosis;
  • fight against the Tendal effect, which creates bluish pigments on the skin after injections with hyaluronic acid;
  • preparation for plastic surgery to remove scars and scars.

Liporase 1,500 I.U of hyaluronidase preparation is presented in the form of a lyophilized powder that contains 1,500 i.u, which is pre-mixed with sterile saline solution. It is important to remember that the product is supplied in pure form without preservatives and should be used immediately after reconstitution. The drug lasts an average of 48 hours.

To get rid of the fibro-sclerotic form of cellulite, Liporase is rarely used today. The course consists of several procedures with a time interval of one week. In one session, up to 3000 units of the drug are injected into the deep layers of the dermis (up to 1 cm).

Hyaluronidase Liporase – perfect shape correction

Despite the fact that hyaluronic acid has a high biocompatibility with human integumentary tissues, there is a risk of granuloma formation as a reaction to a foreign body. The formation of granulomas in the form of redness, local inflammation, and soreness does not occur immediately and can persist for a long time. The fastest and most effective means are injections with Liporase, which “breaks down” the hyaluronic acid polymer into simpler agents that are no longer perceived by the body as foreign.

Adverse reactions after breast liposuction and correction of the “double” chin in the form of fibrosis and hyperemia are effectively eliminated with the help of early fan-shaped administration of Liporeise hyaluronidase (500 – 1500 U). The procedure ends with a light massage for even distribution of the product.

Features of use and application in practice

Any stabilized hyaluronic acid is easily and quickly destroyed by hyaluronidase injections, even after many years of being in the body. The experience and professionalism of a specialist are very important here since an incorrect calculation of the dose of the drug and inaccurate administration lead to undesirable consequences and the destruction of molecules outside the injection zone. There are no exact standards, and the calculation is based on the degree of damage and general data. In any case, a test for an allergic reaction to hyaluronidase Liporase is performed beforehand.

To combat the most unpleasant complication from the use of fillers with hyaluronic acid – necrosis due to vascular embolism, hyaluronidase must be injected as soon as possible. In a day, injections with the drug no longer bring the desired result. Early administration of hyaluronidase reduces the effects of ischemia and reduces the risk of necrosis.

Like any other injectable drug, Liporase hyaluronidase has a number of general contraindications.

It is forbidden to use the enzyme in case of inflammatory or infectious diseases, increased allergic reactions, oncological neoplasms, and hemorrhages. During pregnancy and during breastfeeding, injections with hyaluronidase are possible only in special cases when assessing the ratio of benefits to the mother and risks to the fetus or child. It is necessary to remember the time interval between injections with Liporase and other drugs since hyaluronidase enhances the systemic effect of the latter and can lead to unexpected complications and side effects.

Hyaluronidase is a proteinaceous substance and has antigenic properties, which sometimes leads to local allergic reactions in the form of swelling and redness at the injection site. As a rule, such negative reactions on the skin go away on their own within a few days.


Release form: a vial of 1500 units.

Manufacturer: ColdIt, South Korea.


  • 10 vials Hyaluronidase Liporase
  • instruction.

Storage conditions:

Store in a cool, dark place.

Where to Buy Liporase hyaluronidase 1500 IU?

BeautyDermal offers you to buy Liporase 1500 IU (Hyaluronidase) online at the most affordable and attractive prices on the market. We offer you top-quality authentic products as well as a range of other products for aesthetic medicine:

  • dermal fillers
  • botulinum toxins
  • mesotherapy
  • orthopedics
  • gynecology